Contents: Foreword .... vii Preface .... ix Acknowledgements .... xi 1. The beginnings .... 1 2. Foundations of future career .... 13 3. Oxford. Dorothy Hodgkin, Insulin and much else .... 27 4. A digression. Bonding in Bengaluru, marriage and childbirth in Oxford, family .... 45 5. In a new path with old enthusiasm .... 57 6. Indian Institute of Science. Outline of a lifelong association .... 59 7. Molecular Biophysics Unit, involvement with G.N. Ramachandran and his legacy .... 89 8. Interactions involving small biomolecules, chemical evolution leading to origin of life, ISRO .... 111 9. Induction into the biology community .... 127 10. Initiation and development of macromolecular crystallography in India. Realization of a dream .... 131 11. Bioinformatics and computational biology. A complementary engagement .... 161 12. Crystallography and biophysics communities. Organizational efforts .... 169 13. Involvement with academies, President of INSA .... 189 14. Government agencies, institutions .... 235 15. Engagement with Kerala, the second innings .... 265 16. Second digression on family .... 281 17. Motor Neuron Disorder, winding up with added emphasis on TB proteins .... 291 18. Looking back